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BIO2201 Biochemistry 1

Semester 1, 2012 On-campus Toowoomba
Units : 1
Faculty or Section : Faculty of Sciences
School or Department : Biological & Physical Sciences
Version produced : 30 December 2013

Contents on this page

Staffing

Examiner: Robert Learmonth
Moderator: Mark Lynch

Requisites

Pre-requisite: CHE2120

Other requisites

Recommended Prior Study: BIO1101

Rationale

This course provides an introduction to the major classes of biochemical compounds, their metabolism, and laboratory techniques used to study biochemical processes. The course also forms a basis for studies in other courses in the fields of biology, biomedical science and bioinformatics.

Synopsis

Biochemistry may be considered as the description of life at the molecular level. The chemical and physical nature of structures and functions within living cells is studied. This course allows students to develop an understanding of the major classes of biochemical compounds found in living organisms and the metabolism of these compounds. Study of biochemistry is central to studies in biology, and in particular is related to studies in plant and mammalian physiology, microbiology, genetics, cell and molecular biology and bioinformatics. A series of practical classes is integrated with the lectures to allow students to further develop concepts covered in the lectures, and also to become familiar with use of materials and equipment commonly used in biochemistry laboratories.

Objectives

On completion of this course students will be able to:

  1. demonstrate a knowledge of the major classes of biochemical compounds, including carbohydrates, lipids and proteins;
  2. describe the action of enzymes and their applications metabolism;
  3. demonstrate an awareness of the core metabolic processes which occur in different species (including animals, plants and micro-organisms);
  4. demonstrate familiarity with the integration of metabolic pathways in an organism;
  5. demonstrate an awareness of the applications of biochemistry in contemporary science;
  6. demonstrate familiarity with and competence in applying a range of laboratory techniques and instrumentation used to identify, quantify and study biochemical substances;
  7. carry out qualitative biochemical tests, and quantify reliably a range of common biochemical substances in biological specimens;
  8. generate, analyse, summarise and report biochemical data.

Topics

Description Weighting(%)
1. Biological Macromolecules: structure and chemistry, carbohydrates, lipids, proteins. 25.00
2. Enzymes: structure, mechanisms of action kinetics, allosteric enzymes. 10.00
3. Bioenergetics: energetics of reactions, ATP and other high energy compounds, energy content of carbohydrates, lipids, proteins. 10.00
4. Metabolism: metabolic regulation, glycolysis, gluconeogenesis, Krebs cycle, electron transport chain, oxidative phosphorylation. 47.00
5. Photosynthesis: light reactions, Calvin cycle. 8.00

Text and materials required to be purchased or accessed

ALL textbooks and materials available to be purchased can be sourced from USQ's Online Bookshop (unless otherwise stated). (https://bookshop.usq.edu.au/bookweb/subject.cgi?year=2012&sem=01&subject1=BIO2201)

Please contact us for alternative purchase options from USQ Bookshop. (https://bookshop.usq.edu.au/contact/)

  • Learmonth, R 2011, Biochemistry - practical manual.
    (USQ StudyDesk.)
  • Nelson, DL & Cox, MM 2008, Lehninger principles of biochemistry, 5th edn, WH Freeman, New York.
  • Pechenik, JA 2010, A Short Guide to Writing About Biology, 7th edn, Longman, Boston.

Reference materials

Reference materials are materials that, if accessed by students, may improve their knowledge and understanding of the material in the course and enrich their learning experience.
  • Berg, JM, Tymoczko, JL & Stryer, L 2007, Biochemistry, 6th edn, WH Freeman, New York.
  • Elliott, WH & Elliott, DC 2009, Biochemistry and molecular biology, 4th edn, Oxford University Press, Oxford.
  • Mathews, CK, Van Holde, KE & Ahern, KG 2000, Biochemistry, 3rd edn, The Benjamin/Cummings Publishing Company, California.
  • Osgood, M & Ocorr, K 2008, The absolute, ultimate guide to Lehninger principles of biochemistry - study guide & solutions manual, 5th edn, WH Freeman, New York.
  • Voet, D, Voet, JG & Pratt, CW 2006, Fundamentals of biochemistry, 2nd edn, John Wiley and Sons, New York.

Student workload requirements

Activity Hours
Examinations 2.00
Laboratory or Practical Classes 24.00
Lectures 28.00
Private Study 111.00

Assessment details

Description Marks out of Wtg (%) Due Date Notes
1 HR CLOSED MID SEMESTER TEST 20 20 28 Feb 2012 (see note 1)
PRACTICAL REPORTS 20 20 28 Feb 2012 (see note 2)
2 HR CLOSED EXAM 60 60 End S1 (see note 3)

NOTES
  1. Mid-semester test timetable to be advised in the Practical Manual.
  2. Practical Reports due dates to be advised in the Practical Manual.
  3. Examination dates will be available during the Semester. Please refer to the examination timetable when published.

Important assessment information

  1. Attendance requirements:
    It is the students' responsibility to attend and participate appropriately in all activities (such as lectures, tutorials, laboratories and practical work) scheduled for them, and to study all material provided to them or required to be accessed by them to maximise their chance of meeting the objectives of the course and to be informed of course-related activities and administration. To maximize their chances of satisfying the objectives of the practical component of the course, students should attend and actively participate in the laboratory sessions in the course.

  2. Requirements for students to complete each assessment item satisfactorily:
    To complete each of the assessment items satisfactorily, students must obtain at least 50% of the marks available for each assessment item. (Depending upon the requirements in Statement 4 below, students may not have to satisfactorily complete each assessment item to receive a passing grade in this course).

  3. Penalties for late submission of required work:
    If students submit assignments after the due date without prior approval then a penalty of 5% of the total marks gained by the student for the assignment will apply for each working day late up to ten working days at which time a mark of zero may be recorded. No assignments will be accepted after model answers have been posted.

  4. Requirements for student to be awarded a passing grade in the course:
    To be assured of receiving a passing grade a student must achieve at least 50% of the total weighted marks available for the course.

  5. Method used to combine assessment results to attain final grade:
    The final grades for students will be assigned on the basis of the weighted aggregate of the marks obtained for each of the summative assessment items in the course.

  6. Examination information:
    In a Closed Examination, candidates are allowed to bring only writing and drawing instruments into the examination.

  7. Examination period when Deferred/Supplementary examinations will be held:
    Any Deferred or Supplementary examinations for this course will be held during the next examination period.

  8. University Student Policies:
    Students should read the USQ policies: Definitions, Assessment and Student Academic Misconduct to avoid actions which might contravene University policies and practices. These policies can be found at http://policy.usq.edu.au.

Assessment notes

  1. In order to attend laboratory classes, students must provide and wear appropriate personal protective equipment. This shall include a laboratory coat, closed in shoes, and safety glasses. Such equipment must be approved by supervising staff. Failure to provide and wear the appropriate safety equipment will result in students being excluded from classes.

  2. Students may be required to provide a copy of assignments submitted for assessment purposes. Such copies should be dispatched to the USQ within 24 hours of receipt of a request to do so.

  3. Harvard (AGPS) is the referencing system required in this course. Students should use Harvard (AGPS) style in their assignments to format details of the information sources they have cited in their work. The Harvard (AGPS) style to be used is defined by the USQ Library's referencing guide. http://www.usq.edu.au/library/referencing