BIO2108 Haematology 1
|Semester 1, 2013 On-campus Toowoomba|
|Faculty or Section :||Faculty of Sciences|
|School or Department :||Biological & Physical Sciences|
|Version produced :||17 April 2014|
Examiner: Michael Kotiw
Moderator: John Dearnaley
Pre-requisite: BIO1103 and BIO1104
The aim of this course is to build on the student's understanding of Haematology gained from BIO1103 Pathology Studies. Specifically the course is designed to increase the students understanding of the process of hemopoiesis and to be able to explain the function of the various blood constituents. The course will enable the student to explore the rudiments of how certain disease processes may lead to a change in the numbers and morphology of blood cells.
Detailed analysis of specific disease syndromes, together with discussion of relevant diagnostic and therapeutic options will enable the student to begin to integrate these different fields of study and will enhance their capacity to make critical and informed judgements in a professional setting.
This course builds on the foundations obtained in course BIO1103 Pathology Studies. The course explores the nature of common erythrocytic disorders. The pathophysiology and clinical manifestations of blood disorders, together with an overview of therapeutic options will be investigated. The course will provide a solid background in the discipline so as to prepare candidates to undertake further advanced studies in haematology or to commence work in either a diagnostic or research setting.
On completion of this course students will be able to:
- describe the process of haemopoiesis and explain the function of the various blood constituents;
- explain the association between certain disease processes blood cell morphology, quantity and functionality;
- describe and be able to differentiate between normal and abnormal haemostasis;
- understand the theoretical basis of diagnostic tests used in haematology diagnostic laboratories;
- be able to interpret diagnostic data obtained from haematological tests;
- demonstrate an awareness of the nature of various haematological disorders;
- demonstrate an awareness of therapeutic option available foe the treatment of various haematological disorders;
- investigate relevant literature and prepare technical reports on aspects of Haematology;
- become aware of the safety issues associated with working in a diagnostic haematology laboratory.
An overview of the human haematological system
a. Haemoglobin and heme biosynthesis
b. Erythrocyte structure
c. Erythrocyte antigens
d. Granulocyte biology
e. Lymphocyte biology
The normal haematological system
b. Haemostasis & coagulation
An overview of the haemotological system in disease: pathology, diagnosis and therapy
a. Non malignant white cell disorders
b. Haemostatic & coagulation disorders
c. Introduction to haemotological malignancies
Haemotological diagnostic tests
|5.||Case studies in haemotological disorders||16.00|
|6.||Safety in an haematology diagnostic laboratory||4.00|
Text and materials required to be purchased or accessed
ALL textbooks and materials available to be purchased can be sourced from USQ's Online Bookshop (unless otherwise stated). (https://bookshop.usq.edu.au/bookweb/subject.cgi?year=2013&sem=01&subject1=BIO2108)
Please contact us for alternative purchase options from USQ Bookshop. (https://bookshop.usq.edu.au/contact/)
- There are no texts or materials required for this course.
Buja, ML & Krueger, GRF 2005, Netter's illustrated pathology, Saunders Elsevier, Philadelphia, PA.
Carr, JH & Rodak, BF 2009, Clinical hematology atlas, 3rd edn, Elsevier Saunders, St Louis, USA.
Howard, MR & Hamilton, PJ 2008, Haematology, 3rd edn, Churchill Livingstone, Edinburgh, New York.
Rodak, BF, Fritsma, GA & Doig, K 2007, Hematology: clinical principles & applications, 3rd edn, Elsevier Saunders, St Louis, USA.
Student workload requirements
|Description||Marks out of||Wtg (%)||Due Date||Notes|
|Assignments||40||40||26 Feb 2013||(see note 1)|
|2Hr Closed Exam||60||60||End S1||(see note 2)|
- Examiner to advise the end of semester due date for assignments.
- Examination dates will be available during the Semester. Please refer to the examination timetable when published.
Important assessment information
It is the students' responsibility to attend and participate appropriately in all activities (such as lectures, tutorials, laboratories and practical work) scheduled for them, and to study all material provided to them or required to be accessed by them to maximise their chance of meeting the objectives of the course and to be informed of course-related activities and administration. To maximize their chances of satisfying the objectives of the practical component of the course, students should attend and actively participate in the laboratory sessions in the course. The use of safe procedures in the laboratory will be strictly enforced and continuously monitored to ensure competent performance by students. Students who fail to attend sufficient number of practical sessions (less than 80% of total sessions) may be excluded from completion of the practical course on grounds of safety.
Requirements for students to complete each assessment item satisfactorily:
To satisfactorily complete an individual assessment item a student must achieve at least 50% of the marks or a grade of at least C-. (Depending upon the requirements in Statement 4 below, students may not have to satisfactorily complete each assessment item to receive a passing grade in this course).
Penalties for late submission of required work:
If students submit reports after the due date without prior approval of the examiner then a penalty of 5% of the total marks gained by the student for the report may apply for each working day late late up to ten working days at which time a mark of zero may be recorded. No assignments will be accepted after model answers have been posted.
Requirements for student to be awarded a passing grade in the course:
To be assured of receiving a passing grade a student must achieve at least 50% of the total weighted marks available for the course.
Method used to combine assessment results to attain final grade:
The final grades for students will be assigned on the basis of the weighted aggregate of the marks obtained for each of the summative assessment items in the course.
In a Closed Examination, candidates are allowed to bring only writing and drawing instruments into the examination.
Examination period when Deferred/Supplementary examinations will be held:
Any Deferred or Supplementary examinations for this course will be held during the next examination period.
University Student Policies:
Students should read the USQ policies: Definitions, Assessment and Student Academic Misconduct to avoid actions which might contravene University policies and practices. These policies can be found at http://policy.usq.edu.au.
Harvard (AGPS) is the referencing system required in this course. Students should use Harvard (AGPS) style in their assignments to format details of the information sources they have cited in their work. The Harvard (AGPS) style to be used is defined by the USQ Library's referencing guide. http://www.usq.edu.au/library/referencing
Course lecture and tutorial content will be recorded and provided on Camtasia relay on the basis of 2 lectures and 1 tutorial per week.
Tutorials will be primarily used to explore specific syndromes, case studies and or investigative procedures.
Lectures/tutorials are subject to change if for example, time-tabling falls on public holidays.