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BIO3108 Histopathology 2

Semester 1, 2013 External Toowoomba
Units : 1
Faculty or Section : Faculty of Sciences
School or Department : Biological & Physical Sciences
Version produced : 17 April 2014

Contents on this page

Staffing

Examiner: Michael Kotiw
Moderator: Guang Liu

Requisites

Pre-requisite: BIO2216

Rationale

This course expands the knowledge of human tissue and cell examination provided in BIO2216 Histopathology 1. It is essential that laboratory professionals working in this discipline have an operational in depth understanding of the principles and procedures involved in the collection, processing, screening, and interpretation of normal and abnormal cell and tissue specimens. An understanding of the normal and abnormal morphology of human tissues and cells in relationship to recognized disorders is vital to the diagnosis of a variety of human disease states. Familiarity with modern histological and cytological procedures is also a critical component. Safety in an anatomy/histology laboratory is an essential component of the working environment.

Synopsis

This course explores in greater detail the theoretical basis of histology and cytology provided in BIO2216 Histopathology 1. The course provides a detailed exploration of the histopathology and cytopathology of a range of human diseases using syndrome approach which is supplemented with specific case studies. Students are provided with knowledge of the pathogenesis and associated histopathology of the more common benign and malignant diseases with some emphasis on gynaecological abnormalities. In addition students will gain further knowledge of the process of screening, evaluation and interpretation of histological and cytological specimens. The course is offered in two modules. The first provides an overview of common syndromes, whilst the second provides specific case studies.

Objectives

On completion of this course students will be able to:

  1. Recognize and provide an interpretation of normal and abnormal human cell and tissue structure in specified disease syndromes
  2. Analyse case studies and provide appropriate differential diagnoses
  3. To be able to define the appropriate use of basic and advanced histological , cytological and immunohistochemical protocols for the examination of tissues for specific human tissue and cell specimens
  4. Describe how certain diseases can be diagnosed and differentiated using histological and cytological methods
  5. Examine, interpret and report on case studies of diseased tissues and cells and
    be able to offer differential diagnosis
  6. Investigate relevant literature and prepare technical reports on aspects of Histopathology
  7. Be aware of the safety practices required for working in a anatomy/histology laboratory

Topics

Description Weighting(%)
1. MODULE 1: Histopathology overview
A review of histopathological and cytological and safety practices in the examination of human specimens
8.00
2. Advanced staining protocols and sectioning procedures including frozen sections 8.00
3. Syndromes in pathology:
a. acute inflammation
8.00
4. Syndromes in pathology:
b. chronic inflammation
8.00
5. Syndromes in pathology:
c. atherosclerosis
8.00
6. Syndromes in pathology:
d. thrombosis and embolism
8.00
7. Syndromes in pathology:
e. infarction
8.00
8. MODULE 2: Case studies
An introduction to malignant diseases
4.00
9. An introduction to malignant diseases:
a. Prostatic diseases
8.00
10. An introduction to malignant diseases:
b. Breast malignancies
8.00
11. An introduction to malignant diseases:
c. Colonic malignancies
8.00
12. An introduction to malignant diseases:
d. Lung malignancies
8.00
13. An introduction to malignant diseases:
e. EBV infection and Burkitt’s lymphoma and NPC
4.00
14. An introduction to malignant diseases:
f. HBV and HCV infection and primary liver carcinoma
4.00

Text and materials required to be purchased or accessed

ALL textbooks and materials available to be purchased can be sourced from USQ's Online Bookshop (unless otherwise stated). (https://bookshop.usq.edu.au/bookweb/subject.cgi?year=2013&sem=01&subject1=BIO3108)

Please contact us for alternative purchase options from USQ Bookshop. (https://bookshop.usq.edu.au/contact/)

  • Young B, Lowe J, Stevens A & Heath J 2006, Wheater’s Functional Histology. A Text and Colour Atlas, 5th edn, Churchill Livingstone, Edinburgh.

Reference materials

Reference materials are materials that, if accessed by students, may improve their knowledge and understanding of the material in the course and enrich their learning experience.
  • Junqueira L 2009, Basic Histology Text & Atlas, 12th edn, McGraw-Hill.
  • Kerr JB 2010, Functional Histology, 2nd edn, Mosby Elsevier.
  • V Kumar, AK Abbas & N Fausto 2009, Robbins and Cotran Pathologic Basis of Disease, 8th edn, Elsevier Saunders.
  • V Kumar, R Cotran & S Robbins 2007, Basic Pathology, 8th edn, Saunders & Co.

Student workload requirements

Activity Hours
Examinations 2.00
Lectures 26.00
Private Study 125.00
Tutorials 13.00

Assessment details

Description Marks out of Wtg (%) Due Date Notes
Assignment 40 40 26 Feb 2013 (see note 1)
2HR Closed Exam 60 60 End S1 (see note 2)

NOTES
  1. Examiner will advise the due date of the assignment.
  2. Examination dates will be available during the Semester. Please refer to the examination timetable when published.

Important assessment information

  1. Attendance requirements:
    It is the students' responsibility to attend and participate appropriately in all activities (such as lectures, tutorials, laboratories and practical work) scheduled for them, and to study all material provided to them or required to be accessed by them to maximise their chance of meeting the objectives of the course and to be informed of course-related activities and administration. To maximize their chances of satisfying the objectives of the practical component of the course, students should attend and actively participate in the laboratory sessions in the course.

  2. Requirements for students to complete each assessment item satisfactorily:
    To complete the assignment satisfactorily, students must obtain at least 50% of the marks available for the assignment. To complete the examination and test satisfactorily, students must obtain at least 50% of the marks available for the examination and test. To complete the practical component satisfactorily, students must submit all the nominated practical reports and obtain at least 50% of the marks available.

  3. Penalties for late submission of required work:
    If students submit assignments after the due date without (prior) approval of the examiner then a penalty of 5% of the total marks gained by the student for the assignment may apply for each working day late up to ten working days at which time a mark of zero may be recorded.

  4. Requirements for student to be awarded a passing grade in the course:
    To be assured of receiving a passing grade a student must achieve at least 50% of the total weighted marks available for the course.

  5. Method used to combine assessment results to attain final grade:
    The final grades for students will be assigned on the basis of the weighted aggregate of the marks (or grades) obtained for each of the summative assessment items in the course.

  6. Examination information:
    In a Closed Examination, candidates are allowed to bring only writing and drawing instruments into the examination.

  7. Examination period when Deferred/Supplementary examinations will be held:
    Any Deferred or Supplementary examinations for this course will be held in the fourth week of the semester following this course offering and the examiner will advise students involved in writing of the date time and location of any such examination.

  8. University Student Policies:
    Students should read the USQ policies: Definitions, Assessment and Student Academic Misconduct to avoid actions which might contravene University policies and practices. These policies can be found at http://policy.usq.edu.au.

Assessment notes

  1. Students who obtain an overall passing mark, but who do not perform satisfactorily in an examination, may, at the discretion of the Examiner, be granted a supplementary examination. Students will be granted a deferred examination only if they perform satisfactorily in all other assessment items.

  2. The due date for an assignment is the date by which a student must despatch the assignment to the USQ. The onus is on the student to provide proof of the despatch date, if request by the Examiner. Students must retain a copy of each item submitted for assessment. This must be produced within five days if required by the Examiner.

  3. In order to attend laboratory classes, students must provide and wear appropriate personal protective equipment. This shall include a laboratory coat, closed in shoes, and safety glasses. Such equipment must be approved by supervising staff. Failure to provide and wear the appropriate safety equipment will result in students being excluded from classes.

  4. Harvard (AGPS) is the referencing system required in this course. Students should use Harvard (AGPS) style in their assignments to format details of the information sources they have cited in their work. The Harvard (AGPS) style to be used is defined by the USQ Library's referencing guide. http://www.usq.edu.au/library/referencing