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BIO3206 Medical Microbiology and Immunology 3

Semester 2, 2013 External Toowoomba
Units : 1
Faculty or Section : Faculty of Sciences
School or Department : Biological & Physical Sciences
Version produced : 24 April 2014

Contents on this page

Staffing

Examiner: Michael Kotiw
Moderator: John Dearnaley

Requisites

Pre-requisite: BIO2106

Rationale

The aim of this course is to enhance the student's understanding of medical microbiology and Immunology at an advanced level. This requires a detailed knowledge of the mechanisms of microbial pathogenesis from a classical and molecular perspective, together with a detailed understanding of the host immunological response to infectious and non infectious insults. Detailed analysis of specific disease syndromes, together with discussion of relevant diagnostic and therapeutic options will enable the student to integrate these different fields of study and will enhance their capacity to make critical and informed judgements in a professional setting.

Synopsis

This course further develops concepts provided in BIO2106 Medical Microbiology and Immunology 2. The course focuses on the nature, diagnosis and control of infectious diseases with particular emphasis on diseases in humans caused by bacteria. The course is aimed at enhancing the student's understanding of bacterial pathogenesis at the molecular level. Areas of specific emphasis include the nature of bacterial virulence factors, antibacterial therapy and mechanisms of resistance, paradigms in microbe/host interactions and a system approach to clinical infectious disease syndromes. The course also aims to provide an awareness of a range of viral, fungal and parasitic infections occurring in humans. A detailed analysis of the human immune system is provided to ensure the student has a sound foundation in concepts of human responses to infectious and non infectious insults.

Objectives

On completion of this course students will be able to:

  1. give an overview of examples of major clinical diseases due to infections by bacteria;
  2. demonstrate an understanding of methods available for the diagnosis and characterisation of infectious diseases;
  3. Demonstrate an understanding of human immunological defences against infectious and non infectious insults;
  4. demonstrate an understanding of bacterial virulence factors;
  5. demonstrate an understanding of the nature, mechanisms of activity, appropriate use and limitations of antibacterial chemotherapeutic agents;
  6. demonstrate an understanding of how bacteria become resistant to chemotherapeutic agents;
  7. demonstrate an understanding through case studies, paradigms in host/bacteria interactions;
  8. demonstrate an understanding of the nature, diagnosis and options for management of specified infectious disease syndromes;
  9. become aware of infections causes by a range of viruses, fungi and parasites;
  10. undertake research methods training by completing assignments;
  11. become aware of the range and theory underpinning the use of conventional and molecular laboratory techniques to formulate and solve complex infectious disease problems;
  12. undertake and independently solve complex microbiological problems;
  13. investigate relevant literature and prepare technical reports on aspects of Microbiology;
  14. be aware of infection control measures relevant to a microbiology working environment.

Topics

Description Weighting(%)
1. Overview of infectious diseases in a nosocomial setting 4.00
2. Conventional and molecular diagnostics in infectious diseases 12.00
3. Critical concepts in human immunology 16.00
4. Bacterial pathogenesis 12.00
5. Antimicrobial therapy 8.00
6. Case studies in bacterial infections 12.00
7. Case studies in viral infections 12.00
8. Case studies in fungal infections 8.00
9. Case studies in parasitic infections 8.00
10. Sepsis and associated inflammatory syndromes 8.00

Text and materials required to be purchased or accessed

ALL textbooks and materials available to be purchased can be sourced from USQ's Online Bookshop (unless otherwise stated). (https://bookshop.usq.edu.au/bookweb/subject.cgi?year=2013&sem=02&subject1=BIO3206)

Please contact us for alternative purchase options from USQ Bookshop. (https://bookshop.usq.edu.au/contact/)

  • Mims C, Dockrell HM, Goering R, Roitt I, Wakelin D & Zuckerman M 2004, Medical Microbiology, 3rd edn, Elsevier Mosby.

Reference materials

Reference materials are materials that, if accessed by students, may improve their knowledge and understanding of the material in the course and enrich their learning experience.
  • Alberts, B et al 2002, The molecular biology of the cell, 4th edn, Garland Science, New York.
  • Cioco, R, Sunshine, G & Benjamini, E 2003, Immunology: a short course, 5th edn, Wiley, Davis, Calif.
  • Janeway, C, Travers, P, Walport, A & Schloinchik, M 2005, Immunobiology: the immune system in health and disease, 6th edn, Garland Science, New York.
  • Mandell, GL, Dolin, R & Bennett, JE 2005, Mandell, Douglas and Bennett’s principles and practice of infectious diseases, 6th edn, Churchill Livingstone, New York.
    (Vol 1&2.)
  • Ryan, KJ 2004, Sherris medical microbiology: an introduction to infectious diseases, 4th edn, McGraw Hill, New York.
  • Salyers, AA & Whitt, DD 2002, Bacterial pathogenesis: a molecular approach, 2nd edn, ASM Press, Washington.
    (ISBN 1-55581-171X.)

Student workload requirements

Activity Hours
Examinations 2.00
Online Lectures 26.00
Online Tutorials 26.00
Private Study 120.00

Assessment details

Description Marks out of Wtg (%) Due Date Notes
Assignment 1 20 20 16 Jul 2013 (see note 1)
Assignment 2 20 20 16 Jul 2013 (see note 2)
2HR CLOSED EXAMINATION 60 60 End S2 (see note 3)

NOTES
  1. Examiner to advise the due date for assignment.
  2. Examiner to advise the due date for assignment.
  3. Examination dates will be available during the Semester. Please refer to the examination timetable when published.

Important assessment information

  1. Attendance requirements:
    It is the students' responsibility to attend and participate appropriately in all activities (such as lectures, tutorials, laboratories and practical work) scheduled for them, and to study all material provided to them or required to be accessed by them to maximise their chance of meeting the objectives of the course and to be informed of course-related activities and administration. To maximize their chances of satisfying the objectives of the practical component of the course, students should attend and actively participate in the laboratory sessions in the course. The use of safe procedures in the laboratory will be strictly enforced and continuously monitored to ensure competent performance by students. Students who fail to attend sufficient number of practical sessions (less than 80% of total sessions) may be excluded from completion of the practical course on grounds of safety.

  2. Requirements for students to complete each assessment item satisfactorily:
    To satisfactorily complete an individual assessment item a student must achieve at least 50% of the marks or a grade of at least C-. (Depending upon the requirements in Statement 4 below, students may not have to satisfactorily complete each assessment item to receive a passing grade in this course).

  3. Penalties for late submission of required work:
    If students submit reports after the due date without prior approval of the examiner then a penalty of 5% of the total marks gained by the student for the report may apply for each working day late late up to ten working days at which time a mark of zero may be recorded. No assignments will be accepted after model answers have been posted.

  4. Requirements for student to be awarded a passing grade in the course:
    To be assured of receiving a passing grade a student must achieve at least 50% of the total weighted marks available for the course.

  5. Method used to combine assessment results to attain final grade:
    The final grades for students will be assigned on the basis of the weighted aggregate of the marks obtained for each of the summative assessment items in the course.

  6. Examination information:
    In a Closed Examination, candidates are allowed to bring only writing and drawing instruments into the examination.

  7. Examination period when Deferred/Supplementary examinations will be held:
    No supplementary examinations will be offered in the laboratory component of the course. Any Deferred or Supplementary examinations for this course will be held during the next examination period.

  8. University Student Policies:
    Students should read the USQ policies: Definitions, Assessment and Student Academic Misconduct to avoid actions which might contravene University policies and practices. These policies can be found at http://policy.usq.edu.au.

Assessment notes

  1. In order to attend laboratory classes, students must provide and wear appropriate personal protective equipment. This shall include a laboratory coat, closed-in shoes, and safety glasses. Such equipment must be approved by supervising staff. Failure to provide and wear the appropriate safety equipment will result in students being excluded from classes.

  2. Harvard (AGPS) is the referencing system required in this course. Students should use Harvard (AGPS) style in their assignments to format details of the information sources they have cited in their work. The Harvard (AGPS) style to be used is defined by the USQ Library's referencing guide. http://www.usq.edu.au/library/referencing

Other requirements

  1. All lecture and tutorial content will be delivered on-line.