62320 BIOCHEMISTRY 2

Year	No.	Offer	Mode	Description			Cred. Pts
00	62320 	S2  	D 	BIOCHEMISTRY 2            	1.00

Contents


STAFFING:

Examiner: R. LEARMONTH
Moderator: M. SUTHERLAND

PRE-REQUISITE(S)

62220


RATIONALE:

Biochemistry 2 provides an opportunity to develop the attitudes, concepts and skills initiated in Biochemistry 1 to high levels. It concentrates on the organisation and control of biochemical reactions and properties.


SYNOPSIS:

This unit builds on material in the introductory course, 62220. The unit focuses on integration and control of metabolism in animals, plants and micro-organisms. Control of metabolic reactions is considered from the level of individual enzymes, to cells, to integration of metabolism of the whole organism. The practical component includes a week long workshop during which student-driven projects employ current techniques in biochemistry and bio-technology.


OBJECTIVES:

On successful completion of this unit students will be able
to:

  1. demonstrate a knowledge of the current understanding of the
    structure and function of proteins;
  2. explain the principles governing the regulation of biochemical
    pathways and metabolism at the cellular level and whole
    organism level;
  3. show an understanding of the origin, control and operation of
    hormones;
  4. relate the operation of membranes to structure and function of
    their components;
  5. demonstrate a familiarity with the application and limitations
    of the major analytical tools of the biochemist;
  6. demonstrate an awareness of the application of biochemistry in
    contemporary science, particularly in biotechnology and
    clinical studies.

TOPICS:

 Description                                                    Weighting(%)
  1. Protein structure and functions, packing of secondary 19.00 structures into proteins, prediction and classification of protein structure.

  2. Membranes, structure, functions, transport 23.00

  3. Metabolism - central pathways, glycogen and fatty acid 8.00 metabolism.

  4. Hormones and metabolic control, hormone types and 15.00 cellular modes of action.

  5. Metabolic control at cellular and whole body levels. 27.00 Mammalian regulation of organ metabolism in fed, fasted and diseased states.

  6. Biotechnology and current research. 8.00


TEXT and MATERIALS to be PURCHASED:

Lehninger, A.L., Nelson, D.L. & Cox M.M., 1993, Principles of
Biochemistry
, 2nd edn, Worth Publishers, NY.

Pechenik, J.A. 1993, A Short Guide to Writing About Biology, 2nd
edn, Harper-Collins.


RECOMMENDED REFERENCE MATERIALS:

Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K. & Watson, J.D.
1994, Molecular Biology of the Cell, 3rd edn, Garland Press.

Matthews, C.K. & Van Holde, K.E. 1995, Biochemistry, 2nd edn,
Benjamin Cummings.

Stryer, L. 1995, Biochemistry, 4th edn, Freeman, NY.

Voet, D. & Voet, J.G. 1995, Biochemistry, 2nd edn., John Wiley &
Sons.


STUDENT WORKLOAD REQUIREMENTS:

	ACTIVITY				HOURS
Lectures                                      	28
Laboratory or Practical Classes               	56
Private Study                                 	40
Examinations                                  	3
Assessments                                   	40

ASSESSMENT DETAILS:

No  *F/S Marks     Due        Description                              Wtg(%)    LBL WWW
1   S              PASSIM    REPORTS ON LAB WORK                       30.00     N   N
2   S              WK 9      ESSAY                                     10.00     N   N
3   S              END S2    3 HR CLOSED EXAMINATION                   60.00     N   N

*F=Formative, S=Summative

OTHER REQUIREMENTS:

1    Attendance  at  practicals  is  compulsory.  Practicals  will  be
     scheduled as 4 hours per week in weeks 3-6 of semester and for  5
     full  days  in week 13, the last week of the mid-semester  break.
     The   weekly  sessions  will  comprise  tutorials  and  introduce
     practical exercises in preparation for the workshop. The workshop
     will comprise purification of a plant protein and experiments  on
     mammalian metabolism and membranes. The workshop allows  students
     to  experience  a  real world, full time working environment  and
     includes  project  work not feasible in weekly classes.  It  uses
     students'  time more efficiently and provides relevant laboratory
     training. The concentrated activity results in a reduction in the
     number of weekly practicals.
1.1  Assessment of the practical component will comprise evaluation of
     performance  in  the  laboratory (10%) and of  written  practical
     reports and assignments (20%).
2    Written   reports  on  practical  work  must  be  submitted   for
     correction  no  later than one teaching week  (Normally  7  days)
     after the completion of the experiment in the laboratory.
3    In  accordance  with  University's  Assignment  Extension  Policy
     (Regulation  5.9), the examiner of a unit may grant an  extension
     of  the  due  date of an assignment in extenuating circumstances.
     This  policy  may  be  found in the USQ  Handbook,  the  Distance
     Education  Study  Guide and the Faculty of Sciences'  Orientation
     Handbook for new on-campus students. All students are advised  to
     study and follow the guidelines associated with this policy.
4    Students  must achieve an overall pass of 50%, and at  least  40%
     for  each individual component. Please note that good performance
     in  one or two components may not be sufficient to counterbalance
     weak performance in the remaining component(s).
5    Closed Examination: a closed examination is an examination  where
     the  candidates  are  allowed to bring only writing  and  drawing
     instruments into the examination.

This information is accurate as at 31/10/00