ASSIGNMENT 2

 

CASE STUDY

 

A CASE OF DEMENTIA?

 


Dr. Alvarez is a 62-year-old academic who for the past few years has been concerned about his failing memory. He has had a long and distinguished career as an academic and has taught English Literature in the Faculty of Arts at the local university for the last thirty-two years. He has found life to be considerably less enjoyable since his wife passed away just over eighteen months ago, but has found some solace in his continued love of teaching and the enjoyment he still gets from reading the great classics. Twelve years ago, Dr. Alvarez was the primary caretaker of his ailing father who died of Alzheimer’s disease. He recalls vividly that the first indication he and his wife had that anything was wrong with his father  was a persistent and worsening problem with memory. His father had been an intelligent man who, although poorly educated, had passed on his joy of reading to his son. Dr. Alvarez watched while his father, a robust vital man with a deep appreciation for life, deteriorated into a dependent, frail and confused man before his death. Dr. Alvarez now reports many of the difficulties he observed in his father and is of the opinion that he too may have Alzheimer’s disease. It is for this reason that he has been referred for neuropsychological assessment. Dr. Alvarez was cooperative and appeared highly motivated to perform well. He found the verbal subtests of the WAIS-III particularly easy and made no pronunciation errors at all on the NART-2. You have not been provided with data from his psychosocial assessment but the results of this testing indicated clinically high levels of depression for which he is taking antidepressant medication.

 

Eighteen months following the first assessment, Dr. Alvarez was assessed again using the WAIS-III and WMS-III. Psychosocial testing at this time revealed a substantial reduction in depressive symptomatology. This finding was consistent with his physician’s observation of improvement in his mood and subsequent reduction in dosage of his medication.

 

Presented below are data from two psychological test batteries – the third editions of the Wechsler Adult Intelligence Scale and Wechsler Memory Scale. In a comprehensive assessment many more than these two batteries would be administered but the data presented will be sufficient for you to address the questions in this assignment. In order to complete the assignment you will need to analyse the test data provided, including making a number of statistical comparisons in order to address the most likely hypotheses in the case. These analyses and the other supporting documentation are sufficient to answer the questions posed.

 


Results of Initial Psychological Testing

 

Wechsler Adult Intelligence Scale-Third edition

 

 

Subtest

SS

%ile

 

   Subtest

SS

%ile

Vocabulary   

18

99 

   

   Picture Completion 

14

91  

Similarities   

18

99

   

   Digit Symbol-Coding

  9

37

Arithmetic   

15

95

   

   Block Design 

12

75

Digit Span   

12 

75

   

   Matrix Reasoning   

15

95

Information   

18

99

   

   Picture Arrangement 

15

95

Comprehension   

17

99

   

   Symbol Search    

11

63  

Lett.-Num. Seq.    

12

75

   

   

   

   

 

   

   

   

   

   Test    

   90%CI

   

   Retest

   90%CI

IQs

SS

%ile

 

Low

High

 

Low

High

  Verbal   

144

99.8

    

139

147

   

137

149

  Performance   

121

92

   

114

125

   

111

128

  Full Scale   

138 

99

   

134

141

   

132

142

Indices

   

   

   

   

   

   

    

   

  VCI   

150

99.9

   

143

153

   

141

155

  POI   

123

94

   

115

127

  

112

130

  WMI   

117

87

   

110

122

   

108

124

  PSI   

99

47

   

92

107

   

87

111

Premorbid Estimates of WAIS-III Composites Using Demographic Data

     

90% Confidence Band

Composites

SS

 

Lo

High

Verbal   

125   

 

  108   

  142

Performance   

125   

 

  103   

  147

Full Scale   

120   

 

  102   

  138

Verbal Comprehension   

126   

 

  109   

  144

Perceptual Organisation   

127   

 

  103   

  151

Working Memory   

124   

 

  100   

  149

Processing Speed   

117   

 

    95

   138

WAIS-III Verbal Composites Estimated from NART-2 Error Score of 0

WAIS-III VIQ   

122   

 

  108   

  136

WAIS-III VCI   

119   

 

  106   

  132

 

Wechsler Memory Scale-Third Edition

   

   

   

   

   Test    

   90%CI

   

   Retest

   90%CI

  Indices

SS

%ile

Low

High

Low

High

  Auditory Immediate

102

55

    

96

108

   

93

111

  Visual Immediate   

94

34

   

87

104

   

81

110

  Immediate Memory

98 

45

   

92

105

   

88

108

  Auditory Delayed

89 

23

   

83

98

   

78

104

  Visual Delayed

78

7

   

73

90

   

68

97

  Aud. Rec. Delayed

85

16

   

80

98

  

72

107

  General Memory

81

10

   

76

89

   

72

94

  Working Memory

115

84

   

105

121

   

101

125


Results of Psychological Testing Eighteen Months Later

 

   WAIS-III

   

   WMS-III

Composites

SS

%ile  

   Indices

SS

%ile

Verbal   

138

99

   

Auditory Immediate   

94

34

Performance   

117

87

   

Visual Immediate   

81

10

Full Scale   

132

98

   

Immediate Memory   

86

18

VCI   

145

99.7

   

Auditory Delayed   

74

4

POI   

118

88

   

Visual Delayed

65

1

WMI   

115

84

   

Aud. Rec. Delayed

85

16

PSI   

103

58

   

General Memory

69

  2

   

   

   

   

Working Memory   

108

70

 


 Assignment Questions

 

Answer each of the following questions on a separate page. Your answers will be marked not only on whether or not your answer is correct but also on the quality and reasoning of argument. This means that a well reasoned incorrect answer could receive more marks than an inadequately explained correct answer.

 

 

Question 1:  Describe Dr. Alvarez’ initial test results in terms of the cognitive constructs they are designed to measure., i.e. verbal abilities, visual processing abilities, attention/working memory, processing speed, immediate memory, delayed recall. (5 Marks)

 

Question 2: What are the most likely explanations for Dr. Alvarez’s condition? I do not want you to speculate wildly, but rather consider the alternative hypotheses that have to be tested. (5 Marks)

 

Question 3: Discuss the implications of Dr. Alvarez’s scores on VIQ and VCI particularly with regard to comparisons with other measures on the WAIS-III? What are these scores most likely to reflect? (5 Marks)

 

Question 4: Based upon the test analyses for the first testing is there evidence for a dementing disorder in this case? If yes, explain why. If no, explain why not. (5 Marks)

 

Question 5: What likely diagnosis does the data from the second testing, in association with that of the first testing, indicate? (5 Marks)

 

Question 6: What feedback would you give Dr. Alvarez after the first testing? What would you then say to this gentleman after the second evaluation? (5 Marks)

 


TABLES TO ASSIST IN ANALYSING TEST DATA FOR THIS CASE

 

(All tables have been derived from data published in the WAIS-III/WMS-III Technical Manual published by The Psychological Corporation, San Antonio, 1997 and the respective Tests Manuals)

 

Differences Between IQ Scores and Between Index Scores Required for Statistical Significance at the .05 Level of Significance for the 55 to 64 Age Group

 

VIQ – PIQ

VCI – POI

VCI – WMI

POI – PSI

VCI – PSI

POI – WMI

WMI – PSI

p=.05

7.90

8.54

9.08

11.53

10.91

9.81

11.93

 

Differences Between WMS-III Primary Index Scores for Statistical Significance at the .05 Level of Significance for the 55 to 64 Age Group

 

AI –

VI

AI – AD

VI – VD

AD – ARD

AD – VD

IM - GM

IM – WM

GM – WM

p=.05

15.0

13.8

18.1

19.7

17.1

12.8

13.8

14.1

 


Frequencies of Differences Between WAIS-III IQ and Index Scores for Individuals with FSIQ > 120

 

Difference

Frequency

VIQ – PIQ

23

4.0%

VCI – POI

27

2.9%

VCI – WMI

33

0.8%

POI – PSI

24

6.9%

VCI – PSI

51

<1.3%

POI – WMI

6

34.3%

WMI - PSI

21

12.6%

 

Frequencies of Differences Between WMS-III Primary Index Scores

Comparison

Difference

Frequency

AI – VI

8

32.3%

AI – AD

13

4.5%

VI – VD

16

3.3%

AD – ARD

4

38.7%

AD – VD

11

26.0%

IM – GM

17

1.1%

IM – WM

-17

15.5%

GM – WM

-34

1.7%

 

 


Comparisons of WAIS-III and WMS-III Composites Using Predicted Difference Method (Based Upon a FSIQ of 138).

WMS-III Index

Predicted

Obtained

Difference

p=.05

Frequency

Auditory Immediate

122

102

20

16.9

5%

Visual Immediate

114

94

20

16.9

5-10%

Immediate Memory

122

98

24

17.1

3%

Auditory Delayed

122

89

33

13.7

<1%

Visual Delayed

116

78

38

16.1

<1%

Aud. Rec. Delayed

119

85

34

10.9

<1%

General Memory

123

81

42

15.2

<1%

Working Memory

126

115

11

12.0

15%

 

 


Differences Between Single Subtest Scaled Scores and Mean Scaled Score at the .05 Level of Statistical Significance and Magnitude of Difference Found in 5% of the Standardisation Sample

 

 

Verbal

Subtests

Performance

Subtests

All

Subtests

Subtest

p<.05

5%

p<.05

5%

p<.05

5%

VO

2.10

3.00

 

 

2.30

3.38

SI

2.77

3.29

 

 

3.12

3.69

AR

2.63

3.57

 

 

2.95

3.85

DS

2.40

4.43

 

 

2.67

4.62

IN

2.34

3.29

 

 

2.59

3.69

CO

2.96

3.57

 

 

3.35

3.58

LNS

3.16

4.29

 

 

3.60

4.38

PC

 

 

3.16

3.86

3.46

4.31

CD

 

 

3.04

4.29

3.31

4.46

BD

 

 

2.94

3.71

3.19

3.92

MR

 

 

2.60

3.71

2.75

3.85

PA

 

 

3.75

4.14

4.19

4.46

SS

 

 

3.54

3.86

3.93

4.23

 


Classification of Ability Levels

Classification

Kramer (1990)

Z-Score

WAIS

Subtest

Percentage

included

Lower limit %ile
Very Superior

Significantly above average

+2.0 and above

16 to 19

2.2

98
Superior

Above average

+1.3 to +2.0

14 to 15

6.7

91

High Average

High average

+0.6 to +1.3

12 to 13

16.1

75

Average

Average

-0.6 to +0.6

8 to 11

50.0

25

Low Average

Low average

-1.3 to -0.6

6 to 7

16.1

9

Borderline

Below average

-2.0 to -1.3

4 to 5

6.7

2

Defective Significantly below average -2.0 and below 1 to 3 2.2 -

 

 
WAIS-III QUALITATIVE DESCRIPTIONS FOR IQ SCORE RANGES

 

                                                IQ Score                             Classification              

                                            130 and above                        Very Superior

                                            120-129                                  Superior

                                            110-119                                  High Average

                                            90-109                                    Average

                                            80-89                                      Low Average

                                            70-79                                      Borderline

                                           69 and below                           Extremely Low           

 

 


Friday, 03 May 2002
© 2000 by Graeme Senior, Ph.D.
Senior Lecturer
Department of Psychology
University of Southern Queensland
Toowoomba, QLD 4350
Australia