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The current and official versions of the course specifications are available on the web at https://www.usq.edu.au/course/specification/current.
Please consult the web for updates that may occur during the year.

BIO2217 Transfusion Science

Semester 2, 2020 External
Short Description: Transfusion Science
Units : 1
Faculty or Section : Faculty of Health, Engineering and Sciences
School or Department : School of Health and Wellbeing
Student contribution band : Band 2
ASCED code : 060113 - Pathology
Grading basis : Graded

Staffing

Examiner: Leanne Dooley

Requisites

Pre-requisite: BIO1103 and BIO2108

Rationale

Transfusion Science is a specialised sub-discipline of Haematology focussed on the provision of safe, viable and compatible blood products for patients requiring transfusion. This course will provide students with the theory and practical skills required by health practitioners working in transfusion laboratories and blood banks. Transfusion science will provide. This course will also provide students with a comprehensive understanding of the therapeutic use of blood products in the clinical setting and foster a well-informed systematic approach to the performance of the relevant laboratory investigations.

Synopsis

This course builds on the introduction to Transfusion Science presented in BIO1103 Pathology Studies and the introduction to erythrocyte membranes and red blood cell antigens presented in BIO2108 Haematology 1. Transfusion Science will provide students with a solid understanding of the theory and practice of pre-transfusion testing and the procedures involved in the provision of compatible blood products for patients requiring transfusion of red blood cells, platelets and fresh and fractionated plasma products. This course also explores the pathogenesis and associated laboratory investigation of haemolytic transfusion reactions, haemolytic disease of the foetus and newborn and other serious hazards of transfusion. The isolation, assessment, storage and use of haemopoietic stem cells in transplantation procedures is also explored. The course is designed to enable graduates to commence work in a transfusion laboratory.

The residential school component of this course will provide students with the opportunity to perform a complete pre-transfusion work-up including ABO and Rh(D) blood typing, antibody screening, antibody identification, red blood cell phenotyping and cross-matching. The residential school and associated skills evaluation will enhance the student's capacity and confidence to make critical and informed judgements in a professional setting.

This course contains a mandatory residential school.

Objectives

On completion of this course students will be able to:

  1. describe the nature of the antigens and antibodies of the ABO and Rhesus blood group systems, explain the clinical significance of the major blood group systems in transfusion medicine and demonstrate a deep understanding of ABO and Rh(D) compatibility;
  2. explain the theory of the various laboratory procedures involved in pre-transfusion testing including ABO and Rh(D) blood grouping, antibody screening, antibody identification, red blood phenotyping and cross-matching;
  3. select and perform the appropriate laboratory procedures required for the provision of compatible red blood cells for transfusion;
  4. describe the pathogenesis and laboratory investigation of autoimmune haemolytic anaemia, haemolytic transfusion reactions and haemolytic disease of the foetus and newborn and demonstrate an understanding of the appropriate use of fresh and fractionated blood products in the management of various haematological disorders;
  5. define haemovigilance and patient blood management, discuss the management of blood product inventories, and explain the quality control and quality assurance procedures required for the efficient operation of a hospital blood bank;;
  6. investigate relevant literature and demonstrate a high level of academic, scientific and professional literacy;
  7. demonstrate safe work practices and a clear understanding of the ethical and professional responsibilities associated with working in a transfusion laboratory;

Topics

Description Weighting(%)
1. Introduction to the theory and practice of immunohaematology 12.00
2. The ABO and Rhesus Blood group systems 20.00
3. ABO subgroups and ABO blood group discrepancies and other clinically significant blood group systems 12.00
4. Pre-transfusion testing 20.00
5. Blood and blood products 12.00
6. Haemopoietic stem cell transplantation 12.00
7. Serious hazards of transfusion 12.00

Text and materials required to be purchased or accessed

ALL textbooks and materials available to be purchased can be sourced from USQ's Online Bookshop (unless otherwise stated). (https://omnia.usq.edu.au/textbooks/?year=2020&sem=02&subject1=BIO2217)

Please contact us for alternative purchase options from USQ Bookshop. (https://omnia.usq.edu.au/info/contact/)

Johns, G, Gockel-Blessing, E, Zundel, W & Denesiuk, L 2015, Clinical Laboratory Blood Banking and Transfusion Medicine, Principles and Practice, Pearson Clinical Laboratory Science Series, Pearson Education Inc.
(ISBN. 13-978-0-13-083331-0.)

Reference materials

Reference materials are materials that, if accessed by students, may improve their knowledge and understanding of the material in the course and enrich their learning experience.
Kaushansky, K. & Williams, WJ 2015, Williams hematology, 9th edn, McGraw-Hill, NY.
Overfield, J, Dawson, MM, Hamer, D 2008, Transfusion science, 2nd edn, Scion Publishers, Oxfordshire.
(ISBN 978 1 904842 40 8.)
Rodak BF & Carr, JH 2015, Clinical hematology atlas, 5th edn, Elsevier Saunders, St Louis, USA.
Rodak, BF, Fritsma, GA & Keohane E 2020, Hematology: Clinical principles & applications, 6th edn, Elsevier Saunders, St Louis, USA.

Student workload expectations

Activity Hours
Assessments 20.00
Online Lectures 26.00
Online Tutorials 13.00
Private Study 75.00
Residential Schools 24.00

Assessment details

Description Marks out of Wtg (%) Due Date Notes
Online Quiz 1 20 20 09 Aug 2020 (see note 1)
Assignment 1 20 20 14 Aug 2020 (see note 2)
Online Quiz 2 20 20 27 Sep 2020 (see note 3)
Laboratory Report 20 20 09 Oct 2020 (see note 4)
Online Exam 20 20 End S2 (see note 5)

Notes
  1. The assignment date or written assessment will be available via UConnect when the Alternative Assessment Schedule has been released. Students will be provided further instruction regarding the assignment by their course examiner via StudyDesk.
  2. Examiner to advise the assignment details.
  3. The assignment date or written assessment will be available via UConnect when the Alternative Assessment Schedule has been released. Students will be provided further instruction regarding the assignment by their course examiner via StudyDesk.
  4. Examiner to advise the assignment details.
  5. This will be an open examination. Students will be provided further instruction regarding the exam by their course examiner via StudyDesk. The examination date will be available via UConnect when the official Alternate Assessment Schedule has been released.

Important assessment information

  1. Attendance requirements:
    Students must attend the mandatory residential school. It is the students' responsibility to attend and participate appropriately in all activities (such as lectures, tutorials, laboratories and practical work) scheduled for them, and to study all material provided to them or required to be accessed by them to maximise their chance of meeting the objectives of the course and to be informed of course-related activities and administration. Students must attend the mandatory residential school. (non-attendance will mean the student cannot pass the course). The residential school delivers the practical component for the semester, students must attend and actively participate in the laboratory sessions in the course and maintain a satisfactory record of practical.

  2. Requirements for students to complete each assessment item satisfactorily:
    Due to COVID-19 the requirements for S2 2020 are:
    To satisfactorily complete an individual assessment item a student must achieve at least 50% of the marks for that item.

    Requirements after S2 2020:
    To satisfactorily complete the laboratory report, students must receive 50% of the available marks, and to complete the remaining individual assessment item a student must achieve at least 50% of the marks or a grade of at least C-. (Depending upon the requirements in Statement 4 below, students may not have to satisfactorily complete each assessment item to receive a passing grade in this course).

  3. Penalties for late submission of required work:
    Students should refer to the Assessment Procedure http://policy.usq.edu.au/documents.php?id=14749PL (point 4.2.4).

  4. Requirements for student to be awarded a passing grade in the course:
    Due to COVID-19 the requirements for S2 2020 are:
    To be assured of receiving a passing grade a student must achieve at least 50% of the total weighted marks available for the course.

    Requirements after S2 2020:
    To be assured of receiving a passing grade a student must obtain at least 50% of the total weighted marks available for the course (i.e. the Primary Hurdle), must have satisfied the Secondary Hurdle (Supervised), i.e. the end of semester examination by achieving at least 40% of the marks available for that assessment item, and must have satisfied the Secondary Hurdle (Proficiency), i.e. the laboratory report by achieving at least 50% of the marks available for that assessment item.

  5. Method used to combine assessment results to attain final grade:
    The final grades for students will be assigned on the basis of the weighted aggregate of the marks obtained for each of the summative assessment items in the course.

  6. Examination information:
    Due to COVID-19 the requirements for S2 2020 are:
    An Open Examination is one in which candidates may have access to any printed or written material and a calculator during the examination.

    Requirements after S2 2020:
    In a Closed Examination, candidates are allowed to bring only writing and drawing instruments into the examination.

  7. Examination period when Deferred/Supplementary examinations will be held:
    Due to COVID-19 the requirements for S2 2020 are:
    The details regarding deferred/supplementary examinations will be communicated at a later date.

    Requirements after S2 2020:
    Any Deferred or Supplementary examinations for this course will be held during the next examination period.

  8. University Student Policies:
    Students should read the USQ policies: Definitions, Assessment and Student Academic Misconduct to avoid actions which might contravene University policies and practices. These policies can be found at http://policy.usq.edu.au.

Assessment notes

  1. Harvard (AGPS) is the referencing system required in this course. Students should use Harvard (AGPS) style in their assignments to format details of the information sources they have cited in their work. The Harvard (AGPS) style to be used is defined by the USQ Library's referencing guide. http://www.usq.edu.au/library/referencing

  2. Students should be aware that the originality of any submitted assignment will be checked by the USQ service, "Turnitin". An originality index must be generated and will be checked - an acceptable Turnitin similarity index is <15%.

Other requirements

  1. The dates and location of the mandatory residential school are available from the Residential School Timetable (http://www.usq.edu.au/handbook/current/resschoolsched.html). On-campus students can follow the Class Timetables (https://www.usq.edu.au/current-students/organise-enrolment/timetables/class) as a guide or enrolled students can refer to their student portal and navigate to Student Centre>Self Service>Timetables>My Weekly Schedule.

Date printed 6 November 2020